The season is about getting revenge on and taking down The Company, and features new characters helping them, and hindering them, in their quest. Sarah Wayne Callies returns as Sara Tancredi, who was previously thought to be dead. Season Four of Prison Break is the fourth season of the show, consisting of 22 episodes that aired from Septemto May 15, 2009, with a follow-up TV movie: Prison Break: The Final Break.